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1840 Knickerbocker Sept. 217 The lake itself, along with other portions of the great lake chain, must become a nursery for seamen and ship-building.

1844 in O. L. Holley Picturesque Tourist 195 A vast but secluded country, not yet accommodated with the means of constant and permanent intercourse and traffic with the great lake states.

1851 Hunt's Merchants' Mag. June 700 The northern and southern internal Commerce, extending from the head of the St. Lawrence and Great Lake basin to Mobile.

1857 H. R. Schoolcraft Hist. Indian Tribes U.S. VI. Index 84/2 Great Lakes region, aborigines of.

1881 Ann. Rep. Smithsonian Inst. 1880 79 Great Lakes fishery.

1899 J. B. Mansfield Hist. Great Lakes I. xxvii. 516/1 The districts into which the Great Lakes region was divided.

1929 Pop. Sci. Monthly Sept. 43/2 (caption) Battles with freezing gales are all in the life of the hardy Great Lakes skipper.

1947 C. L. Hubbs & K. F. Lagler Fishes Great Lakes Region 44 Now extinct in the Great Lakes basin.

2007 J. M. Volo & D. D. Volo Family Life in Native Amer. i. i. 11 Those that went east–west along the St. Lawrence Valley and through the Great Lake region gave access to the furs of the western plains.