globulinn.
/ˈɡlɒbjᵿlɪn/, U.S. /ˈɡlɑbjələn/ 1. Botany. Granular material found in plant tissue (as starch granules, chloroplasts, chromoplasts, etc.), formerly believed to constitute an early stage in cell development. Now historical and rare.
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1831 W. Macgillivray tr. A. Richard Elem. Bot. 16 They..are the grains of amylaceous matter..abundantly disseminated through all parts of the vegetable tissue, and to which M. Turpin has recently given the name of globuline.
1852 A. Henfrey tr. H. von Mohl Princ. Anat. & Physiol. Veg. Cell 46 Turpin regarded the granular structures which occur in cells..comprehended by him under the general name of globuline, as vesicles which..grew into cells by subsequent enlargement.
1866 W. T. Brande & G. W. Cox Dict. Sci., Lit. & Art (new ed.) II. 42 Globuline, a term given by Kieser to the green globules lying amongst the cells of cellular tissue.
1999 H. Harris Birth of Cell iii. 35 Turpin accepted..the view that both animal and plant tissues were composed of agglomerations of vesicles, but he..proposed that they were collections of a substance which he named ‘globuline’.
2. Biochemistry. Originally: †the substance that imparts a red colour to blood; haem or haemoglobin (obsolete rare). In later use (as a mass noun): protein belonging to a large and heterogeneous class characterized by solubility in neutral salt solutions but not in water, and often further subdivided by electrophoretic mobility (into alpha, beta, and gamma classes) or sedimentation coefficient. Also (as a count noun): any protein of this class. Frequently with distinguishing word. See also immunoglobulin n.beta, gamma globulin: see the first element.
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the world > life > the body > vascular system > blood > components of blood > blood corpuscle or plate > [noun] > red cells or corpuscles > haemoglobin > forms or parts of
globulin1831
haematosin1834
haemato-crystallin1865
oxyhaemoglobin1869
methaemoglobin1870
globin1872
haematogen1890
methaemoglobulin1890
haemagglutinin1904
haem1925
hypertensinogen1941
angiotensinogen1958
1831 N. Amer. Med. & Surg. Jrnl. 11 255 The author [sc. Lecanu] gives the name of globulin to the colouring matter of the blood, brought to a higher degree of purity than in the state called hematosin.
1845 G. E. Day tr. J. F. Simon Animal Chem. I. 88 In the analysis of the blood, the principal component parts, the water, albumen, hæmatin, globulin and fibrin, are usually determined.
1873 C. H. Ralfe Outl. Physiol. Chem. 27 All the albuminoids are remarkable for their instability..the globulins are the least..stable of the whole group.
1913 J. W. Jenkinson Vertebr. Embryol. iii. 38 The proteins include ovo-vitellin (for the greater part) and some albumin. The former is not a globulin but a nucleo-proteid.
1922 J. J. Sudborough Bernthsen's Text-bk. Org. Chem. (new ed.) xliii. 642 Globulin from the crystalline lens of the eye, fibrinogen from blood; fibrin from clotted blood, and myosin from the plasma of living muscle are globulin derivatives.
1949 H. W. C. Vines Green's Man. Pathol. (ed. 17) ix. 174 Gamma-globulin has been used successfully..against infective hepatitis.
1988 A. M. Silverstein Hist. Immunol. vi. 125 By the 1930s, it was known that antibodies were protein in nature, that they belonged to the class of proteins termed globulins.
2003 U.S. News & World Rep. 10 Feb. 76/2 Only vaccination well ahead of imminent danger will solve the current critical shortage of lifesaving vaccinia immune globulin (VIG).
This entry has been updated (OED Third Edition, September 2009; most recently modified version published online March 2022).
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