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单词 gene silencing
释义

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gene silencing
gene silencing n. the suppression of the expression of a gene, occurring either naturally or as a result of genetic engineering.
ΚΠ
1977 Nature 20 Jan. 259/1 We present evidence of extensive gene silencing in the 50-Myr history of a family of tetraploid species.
1997 Biochemist Feb. 21/2 Because the transgene is identical to the gene already in the plant, it causes gene silencing (co-suppression) and inhibits the expression of the endogenous gene.
2004 Independent 2 Aug. 7/2 This is the first example of targeted gene silencing of a disease gene [sc. Huntington's] in the brains of live animals.
extracted from genen.2
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