galantaminen.

Brit.

/ɡəˈlantəmiːn/, U.S.

/ɡəˈlæn(t)əˌmin/

Forms: 1900s– galantamine, 1900s– galanthamine.

Origin: A borrowing from Latin, combined with an English element; originally modelled on a Russian lexical item. Etymons: Latin Galanthus , amine n.

Etymology: < scientific Latin Galanthus, genus name of the snowdrop ( Linnaeus Species plantarum (1753) I. 288) + amine n., originally after Russian galantamin (M. D. Maškovskij & R. P. Kruglikova-L′vova 1951, in Farmakologija i toksikologija 14 27).

Pharmacology.

An alkaloid, isolated from a species of snowdrop ( Galanthus woronowii) and from related plants, which acts as a selective acetylcholinesterase inhibitor and is used esp. in the treatment of Alzheimer's disease.Galantamine has a tetracyclic structure including a seven-membered ring. Formula: C₁₇H₂₁NO₃.

ΚΠ

1954 N. F. Proskurnina & A. P. Yakovleva in Jrnl. Gen. Chem. U.S.S.R. 22 1941 In the examination of the mother liquors.., we succeeded in isolating a third alkaloid which proved to be a base not previously described in the literature; we have named it galantamine.

1956 Jrnl. Amer. Chem. Soc. 78 4145/2 Galanthamine was identified by its melting point, rotation, analysis [etc.].

1960 Biochem. Pharmacol. 3 147 Galanthamine has been reported to inhibit cholinesterase, to be of benefit in myasthenia gravis, and to increase the sensitivity of muscle to acetylcholine.

1995 New Scientist 11 Feb. 21/1 Galanthamine..has stabilised the symptoms of some patients for up to a year in early trials of the drug.

2004 N.Y. Times Mag. 18 July 38/1 Galantamine has been shown to stimulate a neurotransmitter called acetylcholine, which is thought to heighten cognitive faculties, including those responsible for dreaming.

This is a new entry (OED Third Edition, November 2010; most recently modified version published online March 2022).

单词	galantamine
释义	galantaminen. Brit. /ɡəˈlantəmiːn/, U.S. /ɡəˈlæn(t)əˌmin/ Forms: 1900s– galantamine, 1900s– galanthamine. Origin: A borrowing from Latin, combined with an English element; originally modelled on a Russian lexical item. Etymons: Latin Galanthus , amine n. Etymology: < scientific Latin Galanthus, genus name of the snowdrop ( Linnaeus Species plantarum (1753) I. 288) + amine n., originally after Russian galantamin (M. D. Maškovskij & R. P. Kruglikova-L′vova 1951, in Farmakologija i toksikologija 14 27). Pharmacology. An alkaloid, isolated from a species of snowdrop ( Galanthus woronowii) and from related plants, which acts as a selective acetylcholinesterase inhibitor and is used esp. in the treatment of Alzheimer's disease.Galantamine has a tetracyclic structure including a seven-membered ring. Formula: C₁₇H₂₁NO₃. ΚΠ 1954 N. F. Proskurnina & A. P. Yakovleva in Jrnl. Gen. Chem. U.S.S.R. 22 1941 In the examination of the mother liquors.., we succeeded in isolating a third alkaloid which proved to be a base not previously described in the literature; we have named it galantamine. 1956 Jrnl. Amer. Chem. Soc. 78 4145/2 Galanthamine was identified by its melting point, rotation, analysis [etc.]. 1960 Biochem. Pharmacol. 3 147 Galanthamine has been reported to inhibit cholinesterase, to be of benefit in myasthenia gravis, and to increase the sensitivity of muscle to acetylcholine. 1995 New Scientist 11 Feb. 21/1 Galanthamine..has stabilised the symptoms of some patients for up to a year in early trials of the drug. 2004 N.Y. Times Mag. 18 July 38/1 Galantamine has been shown to stimulate a neurotransmitter called acetylcholine, which is thought to heighten cognitive faculties, including those responsible for dreaming. This is a new entry (OED Third Edition, November 2010; most recently modified version published online March 2022). < n.1954
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