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单词 fluoxetine
释义

fluoxetinen.

Brit. /fluːˈɒksᵻtiːn/, U.S. /fluˈɑksəˌtin/
Origin: Formed within English, by derivation. Etymons: fluoro- comb. form, oxy- comb. form1, methyl n., -ine suffix5.
Etymology: < flu- (in fluoro- comb. form) + ox- (in oxy- comb. form1) + -et- (in methyl n.) + -ine suffix5.
Pharmacology.
A drug that is a selective inhibitor of the reuptake of serotonin, and is commonly used as an antidepressant.Systematic name: N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine; C17H18F3NOA proprietary name for this drug is Prozac n.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > medicine for mental conditions > [noun] > antidepressant > specific drugs
Marsilid1952
iproniazid1953
levallorphan1953
imipramine1958
Tofranil1958
isocarboxazid1959
Marplan1959
Nardil1959
nialamide1959
Niamid1959
phenelzine1959
tranylcypromine1959
Parnate1960
amitriptyline1961
monoamine oxidase inhibitor1962
nortriptyline1962
protriptyline1963
MAOI1965
maprotiline1970
mianserin1970
amoxapine1971
fluoxetine1975
paroxetine1977
Prozac1985
Seroxat1985
1975 Psychopharmacol. Communications 1 511 (title) Analgesic effect of fluoxetine hydrochloride.., a specific inhibitor of serotonin uptake.
1985 Drug Topics 20 May 69/2 Lilly's Prozac (fluoxetine) is an antidepressant with low side effects plus some interesting characteristics, such as appetite suppression and the ability to suppress pain when given with opiates.
1993 Guardian 21 Sept. ii. 16/1 Prozac (known generically as fluoxetine) is the latest US craze, favoured by one in five people who take anti-depressants.
2000 Daily Tel. 11 Jan. 26/2 Prozac's owner..no longer has sole right to the product and Hertfordshire-based Bioglan Pharma yesterday stepped in with a cheaper copy. Bioglan's version uses the same active ingredient—Fluoxetine.
This entry has been updated (OED Third Edition, March 2012; most recently modified version published online March 2022).
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n.1975
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