单词 | fluoroquinolone |
释义 | fluoroquinolonen. Pharmacology. Any of a group of synthetic antibiotics which are fluorinated quinolones, usually also containing a piperazine group, and which typically are well absorbed orally and have broad-spectrum antibacterial activity.Fluoroquinolones act by inhibiting an enzyme involved in the supercoiling of bacterial DNA. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > antibiotics > [noun] > other antibiotics pyocyanase1900 fumigatin1938 M and B1938 gramicidin1940 tyrocidine1940 tyrothricin1940 clavacin1942 fumigacin1942 streptothricin1942 aspergillic acid1943 aspergillin1943 clavatin1943 helvolic acid1943 streptomycin1944 subtilin1944 bacitracin1945 viridin1945 javanicin1946 nisin1947 nitrofurazone1947 polymyxin1947 aureomycin1948 chloramphenicol1949 clitocybin1949 neomycin1949 Terramycin1950 viomycin1950 cephalosporin1951 fumagillin1951 nigericin1951 achromycin1952 carbomycin1952 erythromycin1952 nystatin1952 oxytetracycline1952 tetracycline1952 chlortetracycline1953 nitrofurantoin1953 oligomycin1953 puromycin1953 bacteriocin1954 albomycin1955 spiramycin1955 valinomycin1955 amphotericin B1956 mitomycin1956 novobiocin1956 oleandomycin1956 paromomycin1956 vancomycin1956 kanamycin1957 macrolide1957 ristocetin1957 streptovaricin1957 ethionamide1959 rifamycin1959 strep1959 mithramycin1960 fucidin1961 virginiamycin1961 cephalothin1962 fusidic acid1962 nonactin1962 trimethoprim1962 daunomycin1963 lincomycin1963 anthracycline1964 cephaloridine1964 spectinomycin1964 doxycycline1966 rifampicin1966 minocycline1967 rifampin1968 Adriamycin1969 daunorubicin1969 ribostamycin1970 doxorubicin1971 tobramycin1971 milbemycin1975 fluoroquinolone1984 1984 Jrnl. Antimicrobial Chemother. 26 275 The in vitro activity of the synthetic fluoroquinolone amifloxacin was compared with those of six other antibiotics: ampicillin, aztreonam, cefotaxime, cephalexin, cinoxacin, and gentamicin. 1999 Guardian 19 Aug. i. 4/2 His committee was particularly concerned about the agricultural use of fluoroquinolone, synthetic antibiotics also useful for treating human infections such as E coli, salmonella and typhoid. 2001 Dog Fancy Mar. 31/1 Fluoroquinolones inhibit an enzyme that allows DNA to be properly packaged when bacteria reproduce. Examples: enrofloxacin, orbifloxacin, and marbofloxacin. 2008 Observer 21 Sept. (Food Monthly Suppl.) 59/1 Misuse of the fluoroquinolones is increasingly blamed for the rise in resistance to anti-bacterial medicines. This is a new entry (OED Third Edition, March 2012; most recently modified version published online March 2022). < |
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