| 单词 | androgen insensitivity |
| 释义 | > as lemmasandrogen insensitivity androgen insensitivity n. failure of the body to respond normally to androgens, typically caused by a genetic mutation in the androgen receptor, resulting in a range of intersex conditions from incomplete male sexual development to a fully female appearance in an individual having XY chromosomes (testicular feminization); frequently in androgen insensitivity syndrome. ΚΠ 1963 Amer. Jrnl. Obstetr. & Gynecol. 87 739/2 Among the possible explanations that might account for this discrepancy are..3. End organ failure to respond to androgens or ‘androgen insensitivity’. 1969 Obstetr. & Gynecol. 34 482/1 Androgen insensitivity syndrome, a sex-linked genetic disorder, is characterized by female external appearance, absence of female internal genitalia, cryptorchid testes as gonads, and a 46 XY karyotype. 1993 in M. Haug et al. Devel. Sex Differences & Similarities in Behav. 262 Since the cloning of the human and rat androgen receptors, it has opened the door to eludicating the molecular basis of androgen-insensitivity. 2009 Independent 21 Aug. 19/1 The condition is known as androgen insensitivity syndrome, and very often these women are unaware of it until they try to have children. < as lemmas |
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