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单词 finasteride
释义

finasteriden.

Brit. /fᵻˈnastərʌɪd/, U.S. /fəˈnæstəˌraɪd/
Origin: Apparently formed within English, by derivation. Etymons: an element of unknown origin, steroid n., -ide suffix.
Etymology: < a first element of unknown origin + ster- (in steroid n.) + -ide suffix.
Pharmacology.
A drug that inhibits the conversion of testosterone to the more potent dihydrotesterone in the human prostate gland and hair follicles, used in the treatment of benign prostatic hyperplasia and male-pattern baldness.Chemical name: N-tert-butyl-3-oxo-4-aza-5α-androst-1-ene-17β-carbamate.
ΚΠ
1989 Pharmaceut. Business News 4 Aug. 23/2 MK-906 (Proscar), the 5-alpha reductase inhibitor for use in benign prostatic hyperplasia has been designated finasteride.
1998 Nature 5 Feb. 537/1 Only two treatments have been sanctioned by the US Food and Drug Administration... The other is finasteride (sold as Propecia by Merck & Co.), which is a reduced dosage of a prostate medication that inhibits production of dihydrotestosterone.
2003 C. Wanjek Bad Med. 48 Finasteride entered the arena in the 1990s, marketed as a pill called Propecia... Taken orally, these pills retain hair that would have been lost by inhibiting an enzyme responsible for balding.
This is a new entry (OED Third Edition, March 2007; most recently modified version published online March 2022).
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n.1989
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