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单词 ancrod
释义

ancrodn.

/ˈæŋkrɒd/
Etymology: Probably < modern Latin Agk(ist)rod(on (coined by A. M. F. J. Palisot de Beauvois 1799, in Trans. Amer. Philos. Soc. 4 381), lit. ‘barb-tooth’, < Greek ἄγκιστρον fish-hook + ὀδούς, ὀδοντ-tooth, former genus name of the snake from which the enzyme is obtained, with alteration of -gk- to -nc- following the usual model for Greek transliteration.
Pharmacol.
An anticoagulant protease that lowers the concentration of fibrinogen by cleaving fibrin in the blood, and is given intravenously in the treatment and prevention of some kinds of thrombosis.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations for treating specific parts > [noun] > for the blood > thrombolytics
urokinase1952
thrombolytic1965
ancrod1970
1970 Brit. Med. Jrnl. 5 Dec. 591/1 The defibrinating agent ancrod (Arvin) was used instead of Leparin for intermediate haemodialysis.
1977 Lancet 19 Mar. 625/1 Fifteen patients with severe intermittent claudication were treated by therapeutic defibrination with subcutaneous injections of ancrod for 5 weeks.
1984 New Scientist 25 Oct. 43/1 Ancrod, an anticoagulant derived from the Malayan pit viper.
This entry has not yet been fully updated (first published 1997; most recently modified version published online November 2010).
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n.1970
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