fibrinn.

Brit.

/ˈfʌɪbrɪn/,

/ˈfɪbrɪn/, U.S.

/ˈfaɪbrᵻn/

Forms: Formerly also fibrine, and in Latin form fibrina.

Etymology: < fibre n. + -in suffix¹.

a. Originally: an albuminoid or protein compound substance found in animal matter; coagulable lymph. In modern use: an insoluble protein, formed from fibrinogen during blood clotting, which polymerizes to give the network of the clot.

ΘΚΠ

the world > life > the body > vascular system > blood > components of blood > [noun] > fibrin

coagulable lymph1782

fibrin1800

histin1854

fibrinoid1910

1800 Philos. Trans. (Royal Soc.) 90 375 The substance called fibrin by the chemists.

1802 Med. & Physical Jrnl. 8 297 A disposition to the formation of Fibrina.

1804 W. Nicholson tr. A.-F. de Fourcroy Gen. Syst. Chem. Knowl. IX. 214 (heading) Of the fibrous Part of the Blood, or of the Fibrine.

1813 H. Davy Elements Agric. Chem. vi. 239 Fibrine constitutes the basis of the muscular fibre of animals.

1842 A. Combe Physiol. Digestion (ed. 4) 292 Fibrin is that whitish and tenacious mass which constitutes the solid part of coagulated blood.

1845 London Med. Gaz. 3rd Ser. 1 618/2 The washed clot is the substance which is usually, but very erroneously, named the fibrin of the blood.

1866 H. E. Roscoe Lessons Elem. Chem. xli. 353 The fibrin of flesh appears to differ from that of blood.

1927 R. J. S. McDowall Clin. Physiol. xv. 147 Fibrinogen, which is converted into the fibrin of the clot.

1961 R. G. Macfarlane in Macfarlane & Robb-Smith Functions of Blood vii. 322 During the clotting of fibrinogen, the products are fibrin, which is a polymer formed by union of major residues of the fibrinogen molecules, and fibrinopeptide.

1970 Nature 14 Nov. 669 The conversion of fibrinogen to fibrin..is the last stage of the complex process of blood coagulation.

b. A similar substance in vegetable matter.

ΚΠ

1819 J. G. Children Ess. Chem. Anal. 293 Vegetable fibrin was obtained by Vauquelin from the juice of the papaw tree.

1856 Farmer's Mag. Jan. 2 We give him beans, which abound in fibrine.

1858 E. Lankester & W. B. Carpenter Veg. Physiol. (new ed.) §32 Gluten, fibrin, albumen, caseine, etc., form the basis of all vegetable..tissues.

Compounds

† fibrin-ferment n. [ < German fibrinferment (A. Schmidt 1872, in Arch. f. ges. Physiol. VI. 447)] = thrombin n. Obsolete.

ΚΠ

1876 Jrnl. Chem. Soc. 1 945 The author [sc. Alex Schmidt] proceeds to show..that fibrin-ferment is not a body pre-existing in the blood, which was originally in the red blood corpuscles, and only after its exit from the body passed over into the plasma.

1898 E. A. Schäfer's Text-bk. Physiol. I. 160 Fibrin-ferment (thrombin) or its precursor (prothrombin) producing the formation of fibrin from fibrinogen.

1900 E. H. Starling Elem. Human Physiol. (ed. 4) iii. 78 The coagulation of the blood is due to the conversion of a soluble proteid present in the plasma—fibrinogen, into an insoluble proteid—fibrin, under the agency of a ferment, which is known as fibrin ferment or thrombin.

1923 A. W. Fuller Anæmia i. 8 The blood-plasma is the fluid medium containing..fibrin-ferment, for coagulation purposes.

1951 A. Grollman Pharmacol. & Therapeutics xxviii. 633 Fibrin foam..is an effective hemostatic agent and may be left in situ. It has replaced the fibrin ferments and thromboplastic substances used previously for this purpose.

fibrin film n. a thin sheet of fibrin mixed with a plasticizing agent and used mainly in neurosurgery and to treat burns.

ΘΚΠ

the world > health and disease > healing > medical appliances or equipment > equipment for treating wound or ulcer > [noun] > gauze or oiled silk, etc.

cering-cloth1480

cered cloth1541

cerecloth1547

protective1827

oxycellulose1882

cyanide gauze1895

tulle gras1933

fibrin film1944

1944 Ferry & Morrison in Jrnl. Clin. Investig. XXIII. 566 We shall describe these clots, as well as two kinds of derived products—the fibrin films and fibrinogen plastics—which we have developed from the same proteins.

1968 M. Gerendás in K. Laki Fibrinogen xiii. 294 In essence, fibrin film is a condensed fibrin clot in which the strands are more or less oriented. The film can be stretched and is elastic.

fibrin foam n. a spongy preparation of fibrin used as a hæmostatic in surgery.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > astringent or restringent preparations > [noun] > for stopping bleeding > biological

suprarenalin1901

Stypven1940

fibrin foam1944

1944 Jrnl. Neurosurg. 1 23 A spongy substance, which has been designated as ‘fibrin foam’.

1963 Brit. Pharmaceut. Codex 955 Human Fibrin Foam is a dry artificial sponge of human fibrin. It is prepared by clotting with human thrombin a foam of a solution of human fibrinogen... Human fibrin foam is used..as a hæmostatic agent in surgery.

fibrin-hyaloidin n. (see quot.).

ΚΠ

1920 Jrnl. Chem. Soc. 118 i. 688 Fibrin-hyaloidin obtained from fibrin, C₃₀H₅₄O₂₄N₂, is different from those [sc. hyaloidins] already discussed.

fibrin-peptone n. (see quot.).

ΚΠ

1884 New Sydenham Soc. Lexicon Fibrin-peptone, the peptone resulting from the digestion in gastric juice of fibrine.

This entry has not yet been fully updated (first published 1895; most recently modified version published online March 2022).

单词	fibrin
释义	fibrinn. Brit. /ˈfʌɪbrɪn/, /ˈfɪbrɪn/, U.S. /ˈfaɪbrᵻn/ Forms: Formerly also fibrine, and in Latin form fibrina. Etymology: < fibre n. + -in suffix¹. a. Originally: an albuminoid or protein compound substance found in animal matter; coagulable lymph. In modern use: an insoluble protein, formed from fibrinogen during blood clotting, which polymerizes to give the network of the clot. ΘΚΠ the world > life > the body > vascular system > blood > components of blood > [noun] > fibrin coagulable lymph1782 fibrin1800 histin1854 fibrinoid1910 1800 Philos. Trans. (Royal Soc.) 90 375 The substance called fibrin by the chemists. 1802 Med. & Physical Jrnl. 8 297 A disposition to the formation of Fibrina. 1804 W. Nicholson tr. A.-F. de Fourcroy Gen. Syst. Chem. Knowl. IX. 214 (heading) Of the fibrous Part of the Blood, or of the Fibrine. 1813 H. Davy Elements Agric. Chem. vi. 239 Fibrine constitutes the basis of the muscular fibre of animals. 1842 A. Combe Physiol. Digestion (ed. 4) 292 Fibrin is that whitish and tenacious mass which constitutes the solid part of coagulated blood. 1845 London Med. Gaz. 3rd Ser. 1 618/2 The washed clot is the substance which is usually, but very erroneously, named the fibrin of the blood. 1866 H. E. Roscoe Lessons Elem. Chem. xli. 353 The fibrin of flesh appears to differ from that of blood. 1927 R. J. S. McDowall Clin. Physiol. xv. 147 Fibrinogen, which is converted into the fibrin of the clot. 1961 R. G. Macfarlane in Macfarlane & Robb-Smith Functions of Blood vii. 322 During the clotting of fibrinogen, the products are fibrin, which is a polymer formed by union of major residues of the fibrinogen molecules, and fibrinopeptide. 1970 Nature 14 Nov. 669 The conversion of fibrinogen to fibrin..is the last stage of the complex process of blood coagulation. b. A similar substance in vegetable matter. ΚΠ 1819 J. G. Children Ess. Chem. Anal. 293 Vegetable fibrin was obtained by Vauquelin from the juice of the papaw tree. 1856 Farmer's Mag. Jan. 2 We give him beans, which abound in fibrine. 1858 E. Lankester & W. B. Carpenter Veg. Physiol. (new ed.) §32 Gluten, fibrin, albumen, caseine, etc., form the basis of all vegetable..tissues. Compounds † fibrin-ferment n. [ < German fibrinferment (A. Schmidt 1872, in Arch. f. ges. Physiol. VI. 447)] = thrombin n. Obsolete. ΚΠ 1876 Jrnl. Chem. Soc. 1 945 The author [sc. Alex Schmidt] proceeds to show..that fibrin-ferment is not a body pre-existing in the blood, which was originally in the red blood corpuscles, and only after its exit from the body passed over into the plasma. 1898 E. A. Schäfer's Text-bk. Physiol. I. 160 Fibrin-ferment (thrombin) or its precursor (prothrombin) producing the formation of fibrin from fibrinogen. 1900 E. H. Starling Elem. Human Physiol. (ed. 4) iii. 78 The coagulation of the blood is due to the conversion of a soluble proteid present in the plasma—fibrinogen, into an insoluble proteid—fibrin, under the agency of a ferment, which is known as fibrin ferment or thrombin. 1923 A. W. Fuller Anæmia i. 8 The blood-plasma is the fluid medium containing..fibrin-ferment, for coagulation purposes. 1951 A. Grollman Pharmacol. & Therapeutics xxviii. 633 Fibrin foam..is an effective hemostatic agent and may be left in situ. It has replaced the fibrin ferments and thromboplastic substances used previously for this purpose. fibrin film n. a thin sheet of fibrin mixed with a plasticizing agent and used mainly in neurosurgery and to treat burns. ΘΚΠ the world > health and disease > healing > medical appliances or equipment > equipment for treating wound or ulcer > [noun] > gauze or oiled silk, etc. cering-cloth1480 cered cloth1541 cerecloth1547 protective1827 oxycellulose1882 cyanide gauze1895 tulle gras1933 fibrin film1944 1944 Ferry & Morrison in Jrnl. Clin. Investig. XXIII. 566 We shall describe these clots, as well as two kinds of derived products—the fibrin films and fibrinogen plastics—which we have developed from the same proteins. 1968 M. Gerendás in K. Laki Fibrinogen xiii. 294 In essence, fibrin film is a condensed fibrin clot in which the strands are more or less oriented. The film can be stretched and is elastic. fibrin foam n. a spongy preparation of fibrin used as a hæmostatic in surgery. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > astringent or restringent preparations > [noun] > for stopping bleeding > biological suprarenalin1901 Stypven1940 fibrin foam1944 1944 Jrnl. Neurosurg. 1 23 A spongy substance, which has been designated as ‘fibrin foam’. 1963 Brit. Pharmaceut. Codex 955 Human Fibrin Foam is a dry artificial sponge of human fibrin. It is prepared by clotting with human thrombin a foam of a solution of human fibrinogen... Human fibrin foam is used..as a hæmostatic agent in surgery. fibrin-hyaloidin n. (see quot.). ΚΠ 1920 Jrnl. Chem. Soc. 118 i. 688 Fibrin-hyaloidin obtained from fibrin, C₃₀H₅₄O₂₄N₂, is different from those [sc. hyaloidins] already discussed. fibrin-peptone n. (see quot.). ΚΠ 1884 New Sydenham Soc. Lexicon Fibrin-peptone, the peptone resulting from the digestion in gastric juice of fibrine. This entry has not yet been fully updated (first published 1895; most recently modified version published online March 2022). < n.1800
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