ethisteronen.
/ᵻˈθɪstərəʊn/, U.S. /ᵻˈθɪstəˌroʊn/ Pharmacology.
A synthetic steroid hormone, C21H28O2, which has both androgenic and progestational activity.The first synthetic progestogen, ethisterone has been largely superseded by related substances such as norethisterone (norethindrone).
ΚΠ
1942 Lancet 8 Aug. 174/2 The General Medical Council has approved names for three more substances now being produced, or likely shortly to be produced... Ethisterone.
1947 Brit. Chem. Abstr. A iii. 224 Ethisterone has the following testosterone-like effects: it causes growth of the sex organs in the normal or hypophysectomised castrated immature male rat.
1962 Lancet 25 Aug. 406/2 Amenorone..contains 10 mg. ethisterone (17-α-ethinyl testosterone) and 0.01 mg. œstradiol.
1964 L. C. Martin Clin. Endocrinol. (ed. 4) viii. 246 Ethisterone, a synthetic compound very similar to progesterone, is active by sub-lingual administration but, owing to its feeble progesterone-like action, comparatively large doses must be given.
2001 L. Marks Sexual Chem. ii. 48 Ethisterone..became a key oestrogenic component of oral contraceptives.
This entry has been updated (OED Third Edition, March 2014; most recently modified version published online March 2022).
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n.1942