abasicadj.¹

Brit.

/əˈbeɪzɪk/, U.S.

/əˈbeɪzɪk/

Origin: Formed within English, by derivation; modelled on a French lexical item. Etymons: abasia n., -ic suffix.

Etymology: < abasia n. + -ic suffix, after French abasique (P. Blocq 1888, in Arch. de neurol. 15 211).

Medicine.

Affected with abasia; of or relating to abasia.

ΘΚΠ

the world > health and disease > ill health > a disease > disorders of internal organs > convulsive or paralytic disorders > [adjective] > other convulsive paralysis

akinetic1841

abasic1889

1889 Med. & Surg. Reporter 4 May 534/1 N. (our patient) Abasic. X. (his brother) Ataxic.

1909 S. E. Jelliffe & W. A. White tr. P. Dubois Psychic Treatm. Nerv. Disorders (ed. 6) 380 One sees, on the contrary, astasic and abasic, or rather stasophobic and basophobic symptoms accompanied by other nervous or neurasthenic disorders.

1990 Clin. Neuropathol. 9 262 A 70-year-old man developed an ataxic gait and rapidly progressive disturbance of deep sensation over six months, followed by an abasic state.

This entry has been updated (OED Third Edition, December 2011; most recently modified version published online December 2021).

abasicadj.²

Brit.

/eɪˈbeɪsɪk/, U.S.

/ˌeɪˈbeɪsɪk/

Origin: Formed within English, by derivation. Etymons: a- prefix⁶, basic adj.

Etymology: < a- prefix⁶ + basic adj.

Molecular Biology.

Of a nucleotide: lacking a purine or pyrimidine base. Of DNA, or a specific site in a sequence of nucleotides: containing a nucleotide or nucleotides of this type.

ΚΠ

1982 Mutation Res. 26 263 It therefore appeared from these in vitro studies that DNA polymerases can copy over apurinic sites by insertion of incorrect nucleotides opposite the abasic site.

1990 EMBO Jrnl. 9 3805 (advt.) Eliminate PCR products from a previous reaction by excising uracil residues..and degrading the resulting abasic polynucleotide with heat treatment.

2004 J. Ringo Fund. Genetics 147 An exonuclease removes a short stretch starting with the abasic nucleotide, and DNA polymerase..fills the gap.

2005 Current Biol. 15 616/2 Base hydrolysis generates the so-called abasic sites (AP sites). These noninstructive DNA lesions impede DNA- and RNA-polymerases.

This is a new entry (OED Third Edition, December 2011; most recently modified version published online December 2021).

单词	abasic
释义	abasicadj.¹ Brit. /əˈbeɪzɪk/, U.S. /əˈbeɪzɪk/ Origin: Formed within English, by derivation; modelled on a French lexical item. Etymons: abasia n., -ic suffix. Etymology: < abasia n. + -ic suffix, after French abasique (P. Blocq 1888, in Arch. de neurol. 15 211). Medicine. Affected with abasia; of or relating to abasia. ΘΚΠ the world > health and disease > ill health > a disease > disorders of internal organs > convulsive or paralytic disorders > [adjective] > other convulsive paralysis akinetic1841 abasic1889 1889 Med. & Surg. Reporter 4 May 534/1 N. (our patient) Abasic. X. (his brother) Ataxic. 1909 S. E. Jelliffe & W. A. White tr. P. Dubois Psychic Treatm. Nerv. Disorders (ed. 6) 380 One sees, on the contrary, astasic and abasic, or rather stasophobic and basophobic symptoms accompanied by other nervous or neurasthenic disorders. 1990 Clin. Neuropathol. 9 262 A 70-year-old man developed an ataxic gait and rapidly progressive disturbance of deep sensation over six months, followed by an abasic state. This entry has been updated (OED Third Edition, December 2011; most recently modified version published online December 2021). abasicadj.² Brit. /eɪˈbeɪsɪk/, U.S. /ˌeɪˈbeɪsɪk/ Origin: Formed within English, by derivation. Etymons: a- prefix⁶, basic adj. Etymology: < a- prefix⁶ + basic adj. Molecular Biology. Of a nucleotide: lacking a purine or pyrimidine base. Of DNA, or a specific site in a sequence of nucleotides: containing a nucleotide or nucleotides of this type. ΚΠ 1982 Mutation Res. 26 263 It therefore appeared from these in vitro studies that DNA polymerases can copy over apurinic sites by insertion of incorrect nucleotides opposite the abasic site. 1990 EMBO Jrnl. 9 3805 (advt.) Eliminate PCR products from a previous reaction by excising uracil residues..and degrading the resulting abasic polynucleotide with heat treatment. 2004 J. Ringo Fund. Genetics 147 An exonuclease removes a short stretch starting with the abasic nucleotide, and DNA polymerase..fills the gap. 2005 Current Biol. 15 616/2 Base hydrolysis generates the so-called abasic sites (AP sites). These noninstructive DNA lesions impede DNA- and RNA-polymerases. This is a new entry (OED Third Edition, December 2011; most recently modified version published online December 2021). < adj.¹1889adj.²1982
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abasicadj.1

abasicadj.2

abasicadj.¹

abasicadj.²