dysregulatedadj.
/dɪsˈrɛɡjᵿleɪtᵻd/, U.S. /ˌdɪsˈrɛɡjəleɪdᵻd/ Chiefly Medicine and Psychology.
Abnormally or imperfectly regulated.
ΚΠ
1959 Excerpta Medica: Neurol. & Psychiatry 12 1261 The patients..become active persons who sacrifice themselves, thus partially satisfying the dysregulated urge of self-assertion.
1993 Science 1 Jan. 87/3 The local complement pathway appears to be dysregulated in several models of obesity and can be controlled in cultured adipocytes by certain cytokines, including TNF-α.
2001 A. Solomon Noonday Demon (2002) vi. 234 My dopamine system was dysregulated, and I was anxious, withdrawn, and overwhelmed.
2010 N.Y. Times Mag. 20 June 12/2 The pressures that drive the dysregulated American haven't abated any since the fall of 2008.
This is a new entry (OED Third Edition, June 2014; most recently modified version published online March 2022).
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adj.1959