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单词 dyskaryosis
释义

dyskaryosisn.

Brit. /ˌdɪskarɪˈəʊsɪs/, U.S. /ˈˌdɪskɛriˈoʊsəs/
Origin: Formed within English, by derivation. Etymons: dys- prefix, karyo- comb. form, -osis suffix.
Etymology: < dys- prefix + karyo- comb. form + -osis suffix.
Medicine.
Abnormality of the nucleus of a cell, esp. as an indication of malignant or premalignant change in a vaginal smear or other cytological preparation.
ΚΠ
1951 E. R. Pund & G. R. Lacey in Amer. Surgeon 17 712 A study of the lesions..will frequently demonstrate a sequence of epithelial patterns from hyperplasia to dyskaryosis to neoplasia... Dissociated intra-epithelial anaplasia or dyskaryosis is characterized by..cells with large and sometimes double nuclei.
1981 Brit. Med. Jrnl. 28 Feb. 689/1 These findings emphasise the need for repeat cytological or histological examination in any woman with evidence of dyskaryosis in a cervical smear.
1996 Which? Apr. 17/1 Borderline changes or mild dyskaryosis (about 5.5 per cent)—an early abnormality which can be a sign that pre-cancerous changes are taking place.
2006 Press & Jrnl. (Aberdeen) (Nexis) 27 Jan. 6 It also had the highest number of cases of severe dyskaryosis, a change in cells which is not necessarily harmful in itself but which does require further assessment.
This is a new entry (OED Third Edition, June 2007; most recently modified version published online March 2022).
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n.1951
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