单词 | di-iodo- |
释义 | di-iodo-comb. form Chemistry. Having two atoms of iodine replacing two of hydrogen, as di-iodomethaneCH2I2. ˌdiiodoˈtyrosine n. an iodine-containing derivative of tyrosine, C9H9NO3I2, which is the precursor of thyroxine in the body and the compound into which iodine is first converted when absorbed by the thyroid gland from the blood. ΚΠ 1869 H. E. Roscoe Lessons Elem. Chem. (new ed.) xxxix. 389 Prepared by the action of caustic potash on di-bromo- or di-iodo-salicylic acid. 1877 H. Watts Fownes's Man. Elem. Chem. II. 68 Di-iodomethane..crystallises in colourless shining laminæ of specific gravity 3·34. 1927 Biochem. Jrnl. 21 170 It is highly probable that thyroxine is formed in nature by the coupling of two molecules of diiodotyrosine with the loss of one side chain. 1949 Blakiston's New Gould Med. Dict. 297/2 Diiodotyrosine, C9H9O3NI2. A substance found in skeletons of corals, sponges, and other marine organisms. It..has been used in hyperthyroidism. 1964 L. C. Martin Clin. Endocrinol. (ed. 4) iii. 122 In goitrous cretins..the thyroid may be unable to trap iodide from the blood, or..to couple molecules of diiodotyrosine to form thyroxine. This entry has not yet been fully updated (first published 1896; most recently modified version published online March 2022). < comb. form1869 |
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