diazepamn.
/dʌɪˈazəpam//dʌɪˈeɪzəpam/ Pharmacology.
A minor tranquillizer of the benzodiazepine group with sedative, anticonvulsant, and amnesic properties, given orally and by injection to treat anxiety, muscle spasm, status epilepticus, etc., and sometimes giving rise to withdrawal symptoms when it is discontinued.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > sedatives, antispasmodics, etc. > [noun] > tranquillizer > specific substances or preparations
nepenthes1580
nepenthe1595
Seconal1935
secobarbital1950
mephenesin1952
Largactil1953
Miltown1954
meprobamate1955
hydroxyzine1956
promazine1956
Sparine1956
prochlorperazine1957
Stelazine1958
trifluoperazine1958
Prolixin1959
chlordiazepoxide1960
Librium1960
diazepam1961
Valium1961
oxazepam1964
pimozide1968
lorazepam1969
temazepam1970
alprazolam1973
1961 L. O. Randall et al. in Current Therapeutic Res. III. 405 (caption) Valium (LAIII) (diazepam).
1968 New Scientist 21 Mar. 623/2 Hostile tendencies can often be remarkably controlled by drugs, like Librium and diazepam, which are not sedatives, and which do not depress the general level of cerebral activity.
1977 Sci. Amer. Mar. 53/3 Alcohol, barbiturates and antianxiety drugs, such as chlordiazepoxide (Librium) or diazepam (Valium) seem to share brain mechanisms for tolerance and dependence.
1979 Daily Tel. 29 Nov. 8/8 The big winner at the benzodiazipine tables has been the Swiss firm Roche, which introduced the first drug of this group, chlordiazepoxide, under the brand name Librium in 1960, followed by a variant, diazepam, brand named Valium, three years later.
1981 M. C. Gerald Pharmacol. (ed. 2) xvi. 344 In 1977, 54 million prescriptions were written for diazepam.
This entry has not yet been fully updated (first published 1989; most recently modified version published online June 2018).
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n.1961