degranulationn.
/ˌdiːɡranjʊˈleɪʃən/ Medicine.
The loss or disappearance of (esp. intracellular) granules.
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degranulation1952
1952 Proc. Soc. Exper. Biol. & Med. 80 678/1 Administration of cortisone and acth is followed by more or less marked degranulation.
1961 Nature 9 Sept. 1057/1 Each of the five patients with a history of penicillin anaphylaxis showed significant degranulation of the basophils in the presence of penicillin in vitro.
1964 W. G. Smith Allergy & Tissue Metabolism iii. 35 In tissues situated some distance from the site of injection, the mast cells were not destroyed but showed a sequence of swelling and degranulation followed by a recovery phase.
1974 Nature 6 Dec. 488/2 The estimation of changes inflicted on the endoplasmic reticulum..(such as the in vitro displacement of ribosomes (degranulation) of the liver endoplasmic reticulum by carcinogens).
1986 D. Male Immunol. vi. 88 Degranulation occurs when mast cell granules fuse with the plasma membrane, releasing their contents to the exterior.
This entry has not yet been fully updated (first published 1993; most recently modified version published online March 2019).
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n.1952- to put one's hands unto
- to put one's hands upon
- to put one's head in a noose
- to put one's head on the block
- to put one's heart and soul into
- to put one's heart and soul into something
- to put one's heart into
- to put one's horse at a fence
- to put one's house in order
- to put one's mind to
- to put one's money on
- to put one's money where one's mouth is
- to put one's motty in
- to put one's name into the hat
- to put one's name to
- to put one's neck in a noose
- to risk it
- to risk life and limb
- to risk one's neck
- to rive a person's bonnet
- to rive and rend
- to rive with hunger
- to riverward
- to road hog it
- to road it