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单词 acyclovir
释义

acyclovirn.

Brit. /(ˌ)eɪˈsʌɪkləvɪə/, /(ˌ)eɪˈsɪkləvɪə/, U.S. /eɪˈsaɪkləˌvɪ(ə)r/, /eɪˈsɪkləˌvɪ(ə)r/
Forms: 1900s– aciclovir, 1900s– acyclovir.
Origin: Formed within English, by derivation. Etymons: acyclic adj., -o suffix, viral adj.
Etymology: < acycl- (in acyclic adj.) + -o suffix + vir- (in viral adj.).
Pharmacology.
An antiviral drug used esp. in the treatment of herpes simplex and herpes zoster infections.Acyclovir is a nucleoside analogue. Chemical name: 9-(2-hydroxyethoxymethyl)guanine; C8H11N5O3.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for skin diseases
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acyclovir1979
1979 Antimicrobial Agents & Chemotherapy 15 554/1 The nucleoside analog 9-(2-hydroxyethoxymethyl)-guanosine (acycloguanosine [aciclovir]) has been reported to be an effective and extremely selective agent against several herpes viruses.
1981 Maclean's 2 Nov. 24 The beauty of acyclovir is that it remains inactive in the body until it comes in contact with a herpes-induced enzyme. The enzyme then activates the drug.
1992 New Yorker 5 Oct. 63/3 Nowadays, in addition to taking AZT every four hours, he..takes acyclovir, an antiviral, to bolster the effects of AZT, and takes Bactrim to prevent flareups of pneumonia.
1999 Asda Mag. Aug. 83/3 Once a cold sore appears, a cream called Aciclovir, sold as Zovirax, may ease the pain and help it heal.
2004 J. Playfair Living with Germs (2007) ix. 234 The most vulnerable points inside the cell are those enzymes that only viruses possess, such as the DNA polymerase of herpesviruses, which is blocked by acyclovir.
This entry has been updated (OED Third Edition, December 2011; most recently modified version published online December 2021).
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n.1979
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