| 单词 | aleppo bouton | 
| 释义 | > as lemmasAleppo bouton   Esp. in  Aleppo bouton,  Biskra bouton. The nodular, ulcerated sore that is the characteristic lesion of the protozoal disease cutaneous leishmaniasis, which is endemic in the Middle East, North Africa, and India; the disease itself; = oriental sore n. at oriental adj. and n. Compounds 2. Cf. button n. 7c. Now historical and rare.				 [In Aleppo bouton   apparently after French bouton d'Alep (1780 or earlier).]			 ΚΠ 1846    C. L. Meryon Trav. Lady H. Stanhope I. xvi. 351  				It was not unlikely that the fear of the Aleppo bouton deterred Lady Hester from going also. 1863    Med. Times & Gaz. 14 Feb. 169/1  				The ‘bouton’ of Aleppo, and the ‘bouton’ of Biskra, two endemic diseases of the skin which are still enveloped in much obscurity, are in all probability produced by the use of unwholesome drinking water. 1876    Brit. Med. Jrnl. 19 Feb. 226/1  				Villemin mentions that the ‘boutons on the feet are sometimes multiple, simulating syphilitic ulcers’. 1902    Chambers's Jrnl. 22 Feb. 183/2  				‘Biskra bouton’ is endemic only in the filthy Algerian city from which it derives its name. 2012    Trav. Med. & Infectious Dis. 10 275/1  				The cutaneous manifestation of this disease [sc. leishmaniasis] has a myriad of eponyms based on geographic regions, to include the ‘Aleppo evil’, the ‘Delhi boil’, and the ‘Biskra bouton’. < as lemmas  | 
	
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