| 单词 | cytosine arabinoside |
| 释义 | > as lemmascytosine arabinoside cytosine arabinoside n. a nucleoside composed of cytosine and arabinose, C9H13N3O5, which is an inhibitor of DNA synthesis and is used as an antineoplastic drug, esp. in the treatment of leukaemias. ΚΠ 1961 Federation Proc. (Federation Amer. Soc. Exper. Biol.) 20 357/2 During the growth of the cells, cytosine arabinoside was deaminated to uracil arabinoside and further split to uracil. 1973 R. G. Krueger et al. Introd. Microbiol. xx. 542/2 Cytosine arabinoside..has also been found to inhibit the multiplication of DNA viruses by interfering with DNA synthesis. 2007 Leukemia 21 2399 Cytosine arabinoside (araC), which also generates oxidative stress but does not affect the ATP pool, showed synergism with Aplidin in our leukemia and lymphoma models in vitro and in vivo. < as lemmas |
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