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单词 abzyme
释义

abzymen.

Brit. /ˈabzʌɪm/, U.S. /ˈæbˌzaɪm/
Origin: Formed within English, by compounding. Etymons: antibody n., enzyme n.
Etymology: < a- and -b- (in antibody n.) + -zyme (in enzyme n.).
Biology.
An antibody that has some of the catalytic properties of an enzyme.
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the world > life > biology > substance > process stimulators or inhibitors > antibody > [noun] > types of
Russell body1892
precipitin1900
nephrotoxin1902
hepatotoxin1903
opsonin1903
autoantibody1905
concanavalin1917
isoantibody1919
reagin1925
immune globulin1934
macroglobulin1952
immunoglobulin1953
properdin1954
LATS1961
alloantibody1964
xenoantibody1974
monoclonal1980
abzyme1986
1986 A. Tramontano et al. in Science 19 Dec. 1566/3 We now describe how these antibodies are capable of true enzyme catalysis when their proper substrates are identified. These findings portend the emergence of a class of proteins, having the antibody-enzyme dichotomy, for which the term ‘abzyme’ is suggested.
2000 Sci. News 11 Nov. 318/2 Catalytic antibodies, sometimes called abzymes, have attracted commercial, scientific, and medical interest.
2006 Nature 19 Jan. 247/2 The cellular damage that underlies multiple sclerosis could be caused by an ‘abzyme’—an antibody that acts as an enzyme.
This entry has been updated (OED Third Edition, December 2011; most recently modified version published online December 2021).
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n.1986
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