Creutzfeldt–Jakobn.

/ˌkrɔɪtsfɛltˈjakɒb/

Forms: Also (misspelt) Creutzfeld–Jakob.

Etymology: < the names of Hans G. Creutzfeldt (1885–1964) and Alfons M. Jakob (1882–1927), German neurologists. Compare earlier German Creutzfeldt–Jakobsche Krankheit.

Pathology.

Used attributively and in the possessive, usually in Creutzfeldt–Jakob disease, to designate a communicable progressive disease of the human brain, caused by a prion, in which the degeneration and loss of neurones result in dementia and loss of mobility, and which is accompanied by histological changes characteristic of other spongiform encephalopathies.

ΘΚΠ

the world > health and disease > ill health > a disease > disorders of internal organs > disorders of nervous system > [noun] > disorders of brain > other brain disorders

brain damage1864

mind-blindness1888

satellitosis1906

syringobulbia1908

Alzheimer's disease1911

kernicterus1912

pseudotumour1914

brain death1928

punch-drunk1928

Sturge–Weber syndrome1935

Alzheimer1938

Creutzfeldt–Jakob1939

Alzheimer1940

Schilder's disease1940

hypsarrhythmia1952

kuru1957

laughing death1957

Minamata disease1957

myelinolysis1959

spongiform encephalopathy1960

CJD1975

old-timer's disease1983

mad —— disease1990

the world > health and disease > ill health > a disease > disorders of internal organs > disorders of nervous system > [adjective] > disorders of brain > other brain disorders

hardbound?a1425

bound1704

Wernicke1887

mind-blind1905

Alzheimer1911

Waterhouse–Friderichsen syndrome1934

brain-damaged1946

kernicteric1956

brain-dead1972

C-J1972

hypsarrhythmic1977

flatline1978

Creutzfeldt–Jakob1987

1939 Q. Cumulative Index Medicus 24 1047/1 (title) Creutzfeldt–Jakob's disease (spastic pseudosclerosis).

1957 Jrnl. Neuropath. & Exper. Neurol. 16 134 Several years ago I had the opportunity of studying the microscopical sections of a Norwegian case of Creutzfeld–Jakob disease.

1963 Jrnl. Neuropath. & Exper. Neurol. 22 381 Creutzfeldt–Jakob's disease..shares the following clinical features with Alzheimer's and Pick's diseases.

1985 Times 8 Nov. 13/7 A suspicion that the hormone..might be a source of the virus which causes Creutzfeld–Jakob disease.

1987 Economist 14 Nov. 94/1 Others [sc. examples of slow-virus diseases] include Creutzfelt–Jakob [sic] syndrome and Gerstmann–Straussler syndrome, both mercifully rare.

1993 Guardian 30 Oct. 8/8 He argues that, if man is susceptible to BSE, then at least 8 million adults are likely to have eaten enough to get Creutzfeldt–Jakob Disease (the human form) unless they die first from other causes.

1996 Daily Telgraph 25 Mar. 1 Douglas Hogg, the Agriculture Minister, confirmed his department was actively considering several slaughter options to combat the renewed threat of BSE in the wake of the announcement last week of a possible link with Creutzfeld–Jakob Disease in humans.

This entry has not yet been fully updated (first published 1997; most recently modified version published online December 2020).

单词	creutzfeldt–jakob
释义	Creutzfeldt–Jakobn. /ˌkrɔɪtsfɛltˈjakɒb/ Forms: Also (misspelt) Creutzfeld–Jakob. Etymology: < the names of Hans G. Creutzfeldt (1885–1964) and Alfons M. Jakob (1882–1927), German neurologists. Compare earlier German Creutzfeldt–Jakobsche Krankheit. Pathology. Used attributively and in the possessive, usually in Creutzfeldt–Jakob disease, to designate a communicable progressive disease of the human brain, caused by a prion, in which the degeneration and loss of neurones result in dementia and loss of mobility, and which is accompanied by histological changes characteristic of other spongiform encephalopathies. ΘΚΠ the world > health and disease > ill health > a disease > disorders of internal organs > disorders of nervous system > [noun] > disorders of brain > other brain disorders brain damage1864 mind-blindness1888 satellitosis1906 syringobulbia1908 Alzheimer's disease1911 kernicterus1912 pseudotumour1914 brain death1928 punch-drunk1928 Sturge–Weber syndrome1935 Alzheimer1938 Creutzfeldt–Jakob1939 Alzheimer1940 Schilder's disease1940 hypsarrhythmia1952 kuru1957 laughing death1957 Minamata disease1957 myelinolysis1959 spongiform encephalopathy1960 CJD1975 old-timer's disease1983 mad —— disease1990 the world > health and disease > ill health > a disease > disorders of internal organs > disorders of nervous system > [adjective] > disorders of brain > other brain disorders hardbound?a1425 bound1704 Wernicke1887 mind-blind1905 Alzheimer1911 Waterhouse–Friderichsen syndrome1934 brain-damaged1946 kernicteric1956 brain-dead1972 C-J1972 hypsarrhythmic1977 flatline1978 Creutzfeldt–Jakob1987 1939 Q. Cumulative Index Medicus 24 1047/1 (title) Creutzfeldt–Jakob's disease (spastic pseudosclerosis). 1957 Jrnl. Neuropath. & Exper. Neurol. 16 134 Several years ago I had the opportunity of studying the microscopical sections of a Norwegian case of Creutzfeld–Jakob disease. 1963 Jrnl. Neuropath. & Exper. Neurol. 22 381 Creutzfeldt–Jakob's disease..shares the following clinical features with Alzheimer's and Pick's diseases. 1985 Times 8 Nov. 13/7 A suspicion that the hormone..might be a source of the virus which causes Creutzfeld–Jakob disease. 1987 Economist 14 Nov. 94/1 Others [sc. examples of slow-virus diseases] include Creutzfelt–Jakob [sic] syndrome and Gerstmann–Straussler syndrome, both mercifully rare. 1993 Guardian 30 Oct. 8/8 He argues that, if man is susceptible to BSE, then at least 8 million adults are likely to have eaten enough to get Creutzfeldt–Jakob Disease (the human form) unless they die first from other causes. 1996 Daily Telgraph 25 Mar. 1 Douglas Hogg, the Agriculture Minister, confirmed his department was actively considering several slaughter options to combat the renewed threat of BSE in the wake of the announcement last week of a possible link with Creutzfeld–Jakob Disease in humans. This entry has not yet been fully updated (first published 1997; most recently modified version published online December 2020). < n.1939
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