amoxapinen.

Brit.

/əˈmɒksəpiːn/, U.S.

/əˈmɑksəˌpin/

Forms: 1900s– amoxapine, 1900s– amoxepine (nonstandard).

Origin: Formed within English, by derivation. Etymons: amino- comb. form, oxy- comb. form², English -apine, -epine.

Etymology: < am- (in amino- comb. form) + ox- (in oxy- comb. form²) + -apine, alteration of -epine, suffix denoting a seven-membered ring containing nitrogen (see benzodiazepine n.), after loxapine, the name of an antipsychotic drug of very similar structure (1970).

Pharmacology.

An antidepressant drug of the tricyclic class (see tricyclic adj. 2b).Amoxapine is closely related in structure to the antipsychotic drug loxapine, and shares some of its properties and side effects.Chemical name: 2-chloro-11-(1-piperazinyl)dibenz [b,f] [1,4] oxazepine, C₁₇H₁₆ClN₃O.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > medicine for mental conditions > [noun] > antidepressant > specific drugs

Marsilid1952

iproniazid1953

levallorphan1953

imipramine1958

Tofranil1958

isocarboxazid1959

Marplan1959

Nardil1959

nialamide1959

Niamid1959

phenelzine1959

tranylcypromine1959

Parnate1960

amitriptyline1961

monoamine oxidase inhibitor1962

nortriptyline1962

protriptyline1963

MAOI1965

maprotiline1970

mianserin1970

amoxapine1971

fluoxetine1975

paroxetine1977

Prozac1985

Seroxat1985

1971 Jrnl. Amer. Med. Assoc. 25 Jan. 621/1 Amoxapine.

1989 Pharmaceut. Jrnl. 16 Sept. 316/1 In comparison with other tricyclic antidepressants, amoxapine is more likely to induce seizures and renal failure.

2001 N. C. Andreasen Brave New Brain (2004) ix. 248 These tricyclics have been joined by other agents that are sometimes referred to as atypical, because of their chemical structure and mixed neurochemical profile. They include amoxapine.

This entry has been updated (OED Third Edition, September 2019; most recently modified version published online December 2021).

单词	amoxapine
释义	amoxapinen. Brit. /əˈmɒksəpiːn/, U.S. /əˈmɑksəˌpin/ Forms: 1900s– amoxapine, 1900s– amoxepine (nonstandard). Origin: Formed within English, by derivation. Etymons: amino- comb. form, oxy- comb. form², English -apine, -epine. Etymology: < am- (in amino- comb. form) + ox- (in oxy- comb. form²) + -apine, alteration of -epine, suffix denoting a seven-membered ring containing nitrogen (see benzodiazepine n.), after loxapine, the name of an antipsychotic drug of very similar structure (1970). Pharmacology. An antidepressant drug of the tricyclic class (see tricyclic adj. 2b).Amoxapine is closely related in structure to the antipsychotic drug loxapine, and shares some of its properties and side effects.Chemical name: 2-chloro-11-(1-piperazinyl)dibenz [b,f] [1,4] oxazepine, C₁₇H₁₆ClN₃O. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > medicine for mental conditions > [noun] > antidepressant > specific drugs Marsilid1952 iproniazid1953 levallorphan1953 imipramine1958 Tofranil1958 isocarboxazid1959 Marplan1959 Nardil1959 nialamide1959 Niamid1959 phenelzine1959 tranylcypromine1959 Parnate1960 amitriptyline1961 monoamine oxidase inhibitor1962 nortriptyline1962 protriptyline1963 MAOI1965 maprotiline1970 mianserin1970 amoxapine1971 fluoxetine1975 paroxetine1977 Prozac1985 Seroxat1985 1971 Jrnl. Amer. Med. Assoc. 25 Jan. 621/1 Amoxapine. 1989 Pharmaceut. Jrnl. 16 Sept. 316/1 In comparison with other tricyclic antidepressants, amoxapine is more likely to induce seizures and renal failure. 2001 N. C. Andreasen Brave New Brain (2004) ix. 248 These tricyclics have been joined by other agents that are sometimes referred to as atypical, because of their chemical structure and mixed neurochemical profile. They include amoxapine. This entry has been updated (OED Third Edition, September 2019; most recently modified version published online December 2021). < n.1971
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