单词 | concanavalin |
释义 | concanavalinn. Biochemistry. Either of two globulins (concanavalin A, B) originally isolated from the jack bean; spec. concanavalin A, a powerful agglutinin of blood. ΘΚΠ the world > life > biology > substance > process stimulators or inhibitors > antibody > [noun] > types of Russell body1892 precipitin1900 nephrotoxin1902 hepatotoxin1903 opsonin1903 autoantibody1905 concanavalin1917 isoantibody1919 reagin1925 immune globulin1934 macroglobulin1952 immunoglobulin1953 properdin1954 LATS1961 alloantibody1964 xenoantibody1974 monoclonal1980 abzyme1986 1917 Jones & Johns in Jrnl. Biol. Chem. XXVIII. 68 Fractional precipitation of the globulin obtained from the jack bean..enabled us to isolate two globulins... The globulin obtained in the greatest amount..we have named canavalin. Associated with canavalin was..a second globulin which was less soluble and had a much higher sulfur content. To this globulin we have given the name concanavalin. 1919 J. B. Sumner in Jrnl. Biol. Chem. 37 137 The minute amount of material which crystallizes as needles is slowly soluble in 10 per cent salt solution... The author has named this globulin concanavalin B. The third globulin, crystallizing in bisphenoid form, and present in moderate amount, appears to be insoluble in any but concentrated salt solutions... The author proposes to name this globulin concanavalin A. 1935 Jrnl. Immunol. 29 134 We made solutions of canavalin, concanavalin A, concanavalin B, jack bean proteose, and an amorphous..jack bean protein and found that although some agglutinin was present in all of these solutions the activity was slight in relation to the amount of protein in solution. 1936 Jrnl. Bacteriol. 32 229 Concanavalin A readily agglutinates erythrocytes from pH 5·2 to pH 7·5. 1974 N. Sharon in J. B. Pridham Plant Carbohydrate Biochem. xvi. 237 Immobilized concanavalin A has been used for the isolation of immunoglobulins and of glycoprotein enzymes. 1983 D. J. Weatherall et al. Oxf. Textbk. Med. I. iv. 29/2 The plant lectins concanavalin A and phytohaemagglutinin (PHA) are..activators of T cells which induce markedly polyclonal blast transformation with DNA synthesis, and this effect is used as a broad in vitro test of T cell function. This entry has not yet been fully updated (first published 1989; most recently modified version published online March 2021). < n.1917 |
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