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单词 agonadal
释义

agonadaladj.

Brit. /ˌeɪɡəʊˈneɪdl/, U.S. /ˌeɪɡoʊˈnæd(ə)l/
Origin: Formed within English, by derivation. Etymons: a- prefix6, gonad n., -al suffix1.
Etymology: < a- prefix6 + gonad n. + -al suffix1. Compare gonadal adj. at gonad n. Derivatives.
Medicine and Biology.
Lacking gonads, or functioning gonads; arising from or associated with the congenital or acquired lack of gonads or the hormones produced by the gonads.
ΚΠ
1925 Med. Jrnl. Austral. 31 Oct. 528/2 We look on her condition rather as due to want of activity of the anterior lobe of the pituitary of Lorain Levi type than of agonadal origin.
1955 K. E. Paschkis & A. E. Rakoff in G. Pincus & K. V. Thimann Hormones III. xv. 853 Since in the male the Müllerian system appears to regress under the influence of androgen from the developing testes, is it not possible that many of these essentially agonadal individuals are genetic males?
1981 Jrnl. Steroid Biochem. 14 1223/1 This apparent resistance to the inhibitory action of androgen on gonadotrophin secretion in the agonadal state has also been reported in castrated men.
1991 Lancet 3 Aug. 286/1 Two groups of agonadal women receiving hormone replacement therapy were given embryos created from donors' eggs and partners' semen.
2007 M. H. Johnson Essent. Reprod. (ed. 6) vii. 139 Gonadotrophin levels in agonadal children, for example those with Turner's syndrome.., increase around the expected time of puberty.
This is a new entry (OED Third Edition, September 2012; most recently modified version published online December 2021).
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adj.1925
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