clonidinen.
/ˈklɒnədiːn/, U.S. /ˈklɑnəˌdin/ Pharmacology.
A drug that acts as an alpha2-adrenoreceptor agonist, used in the treatment of hypertension, opiate withdrawal, and a variety of other conditions.Chemical name: 2, 6-dichloro-N-imidazolidine-2-ylideneaniline.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for blood-pressure disorders
Neo-Synephrine1934
Priscol1938
phenylephrine1947
hexamethonium1949
Priscoline1949
methonium1950
hydralazine1952
phentolamine1953
methyldopa1954
pentolinium1954
mecamylamine1955
hydrochlorothiazide1958
pempidine1958
guanethidine1959
hydroflumethiazide1959
thiazide1959
pheniprazine1960
pargyline1961
vasodepressor1961
alpha blocker1965
clonidine1969
prazosin1970
timolol1973
1969 Lancet 26 July 182/1 Lately, a new imidazoline derivative..(‘Catapres’, ‘ST. 155’, clonidine) has been introduced as a hypotensive agent.
1984 Jrnl. Substance Abuse Treatm. 1 289/1 Heroin addicts are detoxified from opiates with clonidine, an alpha 2 agonist, which minimizes the adrenergic firing primarily responsible for the anxiety associated with opiate withdrawal.
1990 Miami Herald 15 Nov. a 23/1 Wineburg may prescribe three types of medicine: nicotine gum; antidepressant drugs, or clonidine, a drug usually used to control blood pressure.
1997 L. Yablonsky Story of Junk 172 ‘Clonidine,’ I answered, licking my lips. Clonidine gives you dry mouth.
2007 New Yorker 9 Apr. 30/1 A fourteen-year-old girl..died from an apparent overdose of Clonidine, a blood-pressure medicine used to sedate hyperactive children.
This is a new entry (OED Third Edition, March 2010; most recently modified version published online March 2022).
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n.1969