单词 | clioquinol |
释义 | clioquinoln. Pharmacology. A halogenated derivative of quinoline that has been used as an antiseptic to treat mild ear infections, intestinal amoebiasis, diarrhoea, and skin infections; 5-chloro-8-hydroxy-7-iodoquinoline, C9H5NOClI. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > antiseptic > [noun] > specific naphthalene1821 carbolic acid1835 creosote1835 Sanitas1878 chlorocresol1886 salol1887 Listerine1889 salufer1894 Airol1895 fluorol1895 thymoform1899 xeroform1901 triformol1907 thymoloform1911 hexamine1914 Eusol1915 flavine1917 proflavine1917 Dakin1920 naphtha1920 methenamine1926 T.C.P.1934 Zephiran1935 leptazol1946 cetrimide1948 nalidixic acid1962 clioquinol1967 crystal violet1996 1967 Martindale's Extra Pharmacopoeia (ed. 25) 577/2 Clioquinol. 1970 Which? July 208/1 There are medicines advertised as helping you avoid diarrhoea. Almost all contain an antiseptic called clioquinol. 1977 Lancet 16 Apr. 859/2 There is no sound evidence for the medical use of clioquinol. 1983 Fortune 11 July 94/1 Japanese courts in 1978 ruled that clioquinol, a drug Ciba-Geigy introduced and sold under the name Entero-Vioform as a cure for diarrhea, caused a disease of the spinal and optic nerves called subacute myelo-optico-neuropathy ( smon). 1989 Nature 16 Mar. 213/1 Clioquinol [is]..a drug sold widely all over the world without manifesting toxicity like that seen in Japan. This entry has not yet been fully updated (first published 1993; most recently modified version published online December 2018). < n.1967 |
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