单词 | chloralamide |
释义 | chloralamiden. A compound that results from a condensation reaction of chloral with an acid amide; spec. chloral formamide, CCl3·CH(OH)·NH· CHO, a mild hypnotic. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > sedatives, antispasmodics, etc. > [noun] > hypnotic > specific drugs codeine1833 codeia1834 chloral1838 paraldehyde1857 hypnone1886 chloralamide1889 sulphonal1889 uralium1889 ural1891 thymacetin1892 chloralose1893 chloretone1899 hedonal1900 veronal1903 Medinal1908 barbitone1914 barbital1919 Sedormid1928 benzodiazepine1934 hexobarbital1941 hexobarbitone1941 glutethimide1955 Placidyl1955 Mogadon1956 chlordiazepoxide1960 nitrazepam1965 flurazepam1968 medazepam1968 lorazepam1969 Rohypnol1971 flunitrazepam1973 triazolam1973 methapyrilene1974 Halcion1975 1889 Lancet 26 Oct. 849/2 The administration of 40 gr. of chloralamide the evening after gave him an unbroken sleep of nine hours. 1889 Lancet 7 Dec. 1192/1 Dr. Langaard of Berlin reviews in the Therapeutische Monatsschrift the present state of our knowledge of the action of chloralamide. 1897 Trans. Amer. Pediatric Soc. 9 168 The treatment consisted of the administration of nervous sedatives, at first chloralamide, to which later was added hyoscine. 1909 T. C. Allbutt & H. D. Rolleston Syst. Med. (ed. 2) VI. 490 I now use chloralamide which, I am told, is safer than chloral; it acts nearly as well. 1963 K. W. Wheeler in Campaigne & Hartung Med. Chem. VI. i. 12 The so-called chloralamides, products of the condensation of chloral with the NH2 of the amide, generally do have some hypnotic activity but not of a high order. This entry has not yet been fully updated (first published 1933; most recently modified version published online December 2018). < n.1889 |
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