the mind > goodness and badness > inferiority or baseness > imperfection > [noun] > an imperfection > a weakness (3)
transferred and figurative.
In particularized uses. A weak point, a circumstance of disadvantage.
(a) a mild eccentricity or mental disturbance in a person; something wrong in one's way of thinking; frequently in to have a screw loose; †(b)…