chorismicadj.

/kəˈrɪzmɪk/

Etymology: < Greek χωρισμός separation + -ic suffix.

Biochemistry.

chorismic acid n. a hydro-aromatic acid, C₆H₅(OH)(COOH)·O·C(CH₂)COOH, which is formed from shikimic acid in bacteria, fungi, and higher plants as a precursor of aromatic amino acids.

ΘΚΠ

the world > matter > chemistry > organic chemistry > organic acids > [noun] > hydro-aromatic acids > named

chorismic acid1964

1964 M. I. Gibson & F. Gibson in Biochem. Jrnl. 90 249/1 As a result of this work a substance with the properties expected..was isolated, identified and named ‘chorismic acid’.

1968 A. White et al. Princ. Biochem. (ed. 4) xxiv. 573 As indicated in the figure, chorismic acid..is a branch point in the synthesis of the aromatic amino acids; conversion to anthranilic acid leads to tryptophan synthesis, while transformation to prephenic acid provides a precursor of phenylalanine and tyrosine.

1992 Jrnl. Org. Chem. 57 178 The mechanism of chorismate mutase, the enzyme which catalyzes the Claisen arrangement of chorismic to prephenic acid, remains a fascinating area for bioorganic research.

This entry has not yet been fully updated (first published 1997; most recently modified version published online June 2018).

单词	chorismic
释义	chorismicadj. /kəˈrɪzmɪk/ Etymology: < Greek χωρισμός separation + -ic suffix. Biochemistry. chorismic acid n. a hydro-aromatic acid, C₆H₅(OH)(COOH)·O·C(CH₂)COOH, which is formed from shikimic acid in bacteria, fungi, and higher plants as a precursor of aromatic amino acids. ΘΚΠ the world > matter > chemistry > organic chemistry > organic acids > [noun] > hydro-aromatic acids > named chorismic acid1964 1964 M. I. Gibson & F. Gibson in Biochem. Jrnl. 90 249/1 As a result of this work a substance with the properties expected..was isolated, identified and named ‘chorismic acid’. 1968 A. White et al. Princ. Biochem. (ed. 4) xxiv. 573 As indicated in the figure, chorismic acid..is a branch point in the synthesis of the aromatic amino acids; conversion to anthranilic acid leads to tryptophan synthesis, while transformation to prephenic acid provides a precursor of phenylalanine and tyrosine. 1992 Jrnl. Org. Chem. 57 178 The mechanism of chorismate mutase, the enzyme which catalyzes the Claisen arrangement of chorismic to prephenic acid, remains a fascinating area for bioorganic research. This entry has not yet been fully updated (first published 1997; most recently modified version published online June 2018). < adj.1964
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