chemoselectiveadj.
/ˌkiːməʊsᵻˈlɛktɪv/, /ˌkɛməʊsᵻˈlɛktɪv/, U.S. /ˌkimoʊsəˈlɛktɪv/, /ˌkɛmoʊsəˈlɛktɪv/ Chemistry.
Of a chemical reaction or procedure: involving a particular functional group in preference to one or more others which are available.
ΚΠ
1976 Tetrahedron 32 926/2 Chemical transformations without the protection of other functional groups may conveniently be classified as being chemoselective or chemospecific.
1985 Science 22 Feb. 913/3 In defining strategies..to construct complex molecules we require synthetic methods that can..perform a wanted structural change and none other (that is, be chemoselective).
2004 W. Carruthers & I. Coldham Mod. Methods Org. Synthesis (ed. 4) i. 25 Chemoselective reduction of the ester group in the presence of the carboxylic amide..gave iridomyrmecin.
Derivatives
chemoseˈlectively adv. Chemistry in a chemoselective manner.
ΚΠ
1978 Tetrahedron Lett. No. 33. 3043 Methyl levulinate..can be allylated chemoselectively only at the keto group but not at the ester group to give a lactone.
2000 A. F. Parsons Introd. Free Radical Chem. vii. 152 Reaction of aryl bromide..with tributyltin hydride chemoselectively breaks the carbon-bromine bond to generate the reactive aryl radical.
This is a new entry (OED Third Edition, December 2008; most recently modified version published online March 2022).
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adj.1976