the world > action or operation > harm or detriment > disadvantage > uselessness > [noun] > that which is useless > typically (2)
= migraine, n.; also in phrases as a type of something useless or unhelpful.
to be in the hole U.S.: to be in (usually financial) difficulties (cf. 3). a hole in the head, esp. in to need (something) like a hole in the head…