transitive. figurative. To damage, to render powerless or essentially incomplete; †to deprive of (obsolete).

To cause to fade or wane, to weaken, enfeeble. Cf. appal, v. 6.

To weaken, impair, diminish. Obsolete.

To render less efficacious.

transferred and figurative. To disable, impair. the action or effectiveness of material objects, mechanical contrivances, etc.

To disturb the normal state, working, or functions of; to put into a disordered condition; to cause to act abnormally.

transitive. To make feeble, weaken.

transitive. To make of no effect; to spoil; to humbug.

figurative. To have an (esp. adverse) effect upon; to damage or weaken. colloquial.