And some experts say that - unless challenged early in life - the immune system mounts an 'inappropriate response' to infections, encouraging leukaemia.

Advocates of cognitive behavioural therapy want to help people redefine how they think about situations, thus making anger an inappropriate response.

It was a stunningly inappropriate response in terms of what we - the public as well as the media - wanted to crown this most extraordinary of cricket matches.

These can lead to learning difficulties, excessive boisterousness and inappropriate responses to social protocol.

This mechanism prevents inappropriate responses to self, as self-peptides will not usually be presented with suitable co-stimulation.