These loci provide points along each chromosome which enable a pair of chromosomes to align correctly with each other before separating during meiosis.

If the cut edges did not align correctly or the gluing was not done well, there might still be water leakage along the seam.

The operator may be required to manually control the spin of the ride such that the ride's exit aligns correctly with the exit gate.

In any event boreholes that are not aligned correctly which are then loaded with high explosive can be extremely dangerous, resulting in rock being projected beyond the intended site.

In order for the final device to function correctly, these separate patterns must be aligned correctly - for example contacts, lines and transistors must all line up.