It's hard to overestimate the deleterious effect this sort of thing can have on an actor.

Loss of this priceless example of before-andafter will have a deleterious effect on their professional development.

Removing this incentive will have a deleterious effect on recruitment into many of the professions upon which the public must rely.

Such a fracturing could lead to declines in the participation rates of the amateur game - something that would have an unambiguously deleterious effect on public health.

There was publicity to be had, the trophy to be shown off, but the deleterious effect on some went way beyond what could ever have been envisaged.

Again, this behaviour can have a deleterious impact on any future prosecution and forensic evidence can be lost or destroyed.

They are apparently absorbing the microparticles from the surrounding environment and directing them straight into our gullets (with an inevitably deleterious impact on our physiology).

It's the deleterious impact on inward investment.

However, property speculators and management companies are in the business of profit, and this often has a deleterious impact on residents.

Widespread smoking also has a deleterious impact on health.