Many are deeply embarrassed and in deep despair at having to accept charity.

But he had no idea that the next three years of his life were going to be thrown into complete chaos, spiralling him into deep despair.

Finder's skills in music were such that his songs transcended mere music, inspiring others to great works, renewed vigor or deep despair.

She dismisses his renewed attempts at writing as insubstantial and hackneyed, plunging him into a state of deeper despair.