The 'careless' - those who do not care, or do not care enough - are, in this respect, often credited with a causative role in language change.

Their causative role has been established in some of these diseases but not all.

This condition was dubbed analgesic nephropathy and was attributed to phenacetin, although no absolute causative role was demonstrated.

In order to prove a causative role, it will be important to define the molecular mechanisms through which cadmium in low exposure can cause adverse health effects.

The causative roles of bacteria in tuberculo-sis, leprosy and diphtheria were also discovered in the early days of the new medical science, as were the common bacteria staphylococci and streptococci.