dys·pho·ri·a 
(dĭs-fôrē-ə)
(dĭs-fôrē-ə)n.
An emotional state characterized by anxiety, depression, or unease.
[New Latin, from Greek dusphoriā, distress, from dusphoros, hard to bear : dus-, dys- + -phoros, -phorous.]
dys·phoric (-fôrĭk) adj.