de·pop·u·late 
(dē-pŏpyə-lāt′)
(dē-pŏpyə-lāt′)tr.v. de·pop·u·lat·ed, de·pop·u·lat·ing, de·pop·u·lates
To reduce sharply the population of, as by disease, war, or forcible relocation.
[Latin dēpopulāri, dēpopulāt-, to lay waste : dē-, de- + populārī, to ravage (from populus, people, throng).]
de·pop′u·lation n.
de·popu·la′tor n.