Creutz·feldt-Ja·kob disease 
(kroitsfĕlt-yäkôp)
(kroitsfĕlt-yäkôp)n. Abbr. CJD
A fatal degenerative disease of the brain, caused by a prion and marked by progressive dementia and gradual loss of muscle control. Also called Jakob-Creutzfeldt disease.
[After Hans G. Creutzfeld (1883-1964) and Alfons M. Jakob (1884-1931), German psychiatrists.]