1. A bitter, alkaline, brownish-yellow or greenish-yellow fluid that is secreted by the liver, stored in the gallbladder, and discharged into the duodenum and aids in the emulsification, digestion, and absorption of fats. Also called gall¹.

2. Bitterness of temper; ill humor; irascibility.

3. Either of two bodily humors, black bile or yellow bile, in ancient and medieval physiology.