1. (also sän′tä fĕ) A city of northeast Argentina on the Salado River northwest of Buenos Aires. Founded in 1573, it is a port with various light industries.

2. The capital of New Mexico, in the north-central part of the state northeast of Albuquerque. The Spanish established a settlement here c. 1609 on the site of ancient Native American ruins and developed it as a trade center over the next 200 years. Occupied by US forces in 1846, it became territorial capital in 1851 and state capital in 1912.