an·ti·his·ta·mine 
(ăn′tē-hĭstə-mēn′, -mĭn, ăn′tī-)
(ăn′tē-hĭstə-mēn′, -mĭn, ăn′tī-)n.
Any of various drugs used to counteract the physiological effects of histamine production in allergic reactions and colds.
an′ti·his′ta·minic (-mĭnĭk) adj.