1. Of or relating to the United States of America or its people, language, or culture.

2. Of or relating to North or South America, the West Indies, or the Western Hemisphere.

3. Of or relating to any of the Native American peoples.

4. Indigenous to North or South America. Used of plants and animals.

1. A native or inhabitant of America.

2. A citizen of the United States.

3. American English.