1. A historic section of London, England. It includes Hampton Court Palace, built by Cardinal Wolsey in 1515 and appropriated by Henry VIII around 1526. George II was the last to use it as a royal residence, and much of the palace is now open to the public.

2. An independent city of southeast Virginia opposite Norfolk on Hampton Roads, the outlet of three rivers into Chesapeake Bay. Settled by colonists from Jamestown in 1610, the city was sacked by the British in the War of 1812 and was almost burned to the ground by Confederates in 1861 to prevent its occupation by Union troops.