grief 
(grēf)
(grēf)n.
1.
a. Deep mental anguish, as that arising from bereavement, or an instance of this. See Synonyms at regret.
b. A source or cause of deep mental anguish: "That knowledge would be a grief to her" (Tobias Wolff).
2.
a. Annoyance or frustration, or an instance of this: Trying to follow their directions was nothing but grief.
b. Trouble or difficulty, or an instance of this: the griefs of trying to meet a deadline.
c. Informal Criticism or rude talk: gave me a lot of grief about being late.
3. Archaic A grievance.
[Middle English, from Old French, from grever, to harm, aggrieve; see GRIEVE.]