释义 |
coagulin Biol.|kəʊˈægjuːlɪn| [f. coagulate v.: see -in1.] A name for any of various real or postulated substances that are produced in the body and accelerate the coagulation of foreign proteins or of blood; esp. a thromboplastin or a precipitin.
[1899J. Bordet in Ann. Institut Pasteur XIII. 240 Si nous sommes autorisés à donner désormais à la substance active du sérum, non plus le nom d'agglutinine, qui se borne à indiquer le fait..mais l'appellation plus suggestive de ‘coaguline’,—nous pouvons supposer que les organismes..seront à même d'élaborer..des principes agglomérants actifs.] 1903Med. News LXXXIII. 212/1 (title) On the presence of specific coagulins in the tissues of vertebrates and evertebrates. 1907E. H. Starling Elem. Human Physiol. (ed. 8) iii. 87 Almost any protein, injected into an animal's veins, evokes the production in the animal of an antibody, a coagulin, which has the property of inducing a precipitate in solutions of the protein. 1911J. A. Mandel tr. Hammarsten's Textbk. Physiol. Chem. (ed. 6) vi. 307 The tissues contain..coagulins, which are not identical with the coagulins of the clot or the blood serum. 1917A. P. Mathews Physiol. Chem. (ed. 2) xii. 516 The substances in tissue extracts thus accelerating clotting are sometimes called thromboplastic substances, thrombokinase, tissue fibrinogens, or coagulins. 1929Encycl. Brit. III. 898/1 [Jules Bordet] has thrown light on the process of the formation of coagulin, showing that it includes two elements; the first, albuminoidal and peculiar to the liquid blood, and the other, lipoidal in nature, originating in the cells of the blood or tissues. 1937Proc. Sect. Sci. K. Akad. Wetensch. Amsterdam XL. 221 The secretion of the stomach of Th. annulata contains a strong coagulin. When mixed with blood it has a marked accelerating action on coagulation. 1963I. F. & W. D. Henderson Dict. Biol. Terms (ed. 8) 108/1 Coagulin, any agent capable of coagulating albuminous substances. |