| 释义 |
pyrimidine Chem.|pɪˈrɪmɪdiːn, paɪər-|
Also † -in.
[ad. G. pyrimidin (A. Pinner 1885, in Ber. d. Deut. Chem. Ges. XVIII. 760) f. pyridin pyridine with inserted -im (f. imid imide).]
A colourless, crystalline basic solid, CH:N·CH:N·CH:CH ; any substituted derivative containing this ring structure, spec. cytosine, thymine, or uracil, pyrimidines found in nucleic acids, etc. Freq. attrib.
1885Jrnl. Chem. Soc. XLVIII. ii. 751 The author substitutes the formula R·C{btr1}{bbr2}N·C(OH)N:CMe{bbr2}{btr1}CH for that previously assigned, terming the nucleus pyrimidine. 1886Ibid. L. 45 The author has tried to prepare the corresponding pyrimidines from various amidines. 1899Ibid. LXXVI. i. 639 Pyrimidine..melts at 20–22°..; it has a penetrating, stupefying odour. 1924Nature 12 Apr. 524/1 In these bodies [sc. the nucleic acids] a carbohydrate group is associated with a phosphoric acid group and also with a purin or pyrimidin base. 1947Sci. News IV. 109 The I.C.I. men started on something quite different: the pyrimidine ring, an assemblage of atoms found in uric acid, in the chromosomes of the nucleus of living cells, and widely in all living things. 1952,1954[see purine]. 1960New Biol. XXXI. 40 The two pyrimidines, which are smaller molecules than the purines, are named thymine and cytosine. 1962D. J. Brown Pyrimidines iv. 116 Until recently, pyrimidine was an exceedingly rare substance, but several good methods of preparation have now made it readily available in quantity. 1976Ann. Rev. Microbiol. XXX. 92 Other auxotrophs such as those requiring amino acids, purines, and pyrimidines do not assume a colonial or semicolonial growth habit if the biochemical supplement in the medium is limiting. |