| 释义 |
scopolamine Chem. and Pharm.|skəˈpɒləmiːn|
Formerly also -in.
[ad. G. skopolamin (E. Schmidt 1891, in Apotheker Zeitung VI. 522): see scopol- and amine.]
A syrupy liquid alkaloid, C17H21NO4, having powerful narcotic and sedative properties, which is found in plants of the family Solanaceæ, notably the thorn-apple, Datura stramonium; hyoscine.
1892Jrnl. Chem. Soc. LXII. ii. 1255 Inasmuch as the name hyoscine has been misapplied to tropine, it has become somewhat ambiguous, and the author [sc. E. Schmidt] proposes to call the hyoscine from hyoscyamus, scopolamine, a name which is in accord with the recent isolation of this alkaloid from Scopolia atropoïdes. 1899Allbutt's Syst. Med. VI. 837 Dilatation of the pupil..dependent..upon..the application of some drug (atropine,..scopolamine, etc.). 1925F. J. Reynolds Marvels of 1924 44 Dr. R. E. House has experimented with inmates of prisons, who were reduced by scopolamin to a state in which only their memories functioned. 1940R. Chandler Farewell, My Lovely xxxiii. 156 There's a drug called scopolamine, truth serum, that sometimes makes people talk without their knowing it. 1945A. Huxley Let. 13 Oct. (1969) 535 The adumbrations of future possibilities are to be seen in the practices of contemporary dictatorships—..use of scopolamine and other drugs to extract confessions and make people more susceptible to propaganda, [etc.]. 1976Smythies & Corbett Psychiatry vii. 140 Many proprietary sleeping pills..contain small doses of scopolamine. 1977Lewis & Elvin-Lewis Med. Bot. ix. 223/2 Datura fastuosa and D. metel are abundant sources of scopolamine. 1981T. Barling Bikini Red North v. 114 Sedating her with enough scopolamine to keep her comatose. |